Serveur d'exploration Chloroquine

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888.

Identifieur interne : 000210 ( France/Analysis ); précédent : 000209; suivant : 000211

New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888.

Auteurs : Luke Mani ; Valerie Jullian ; Beatrice Mourkazel ; Alexis Valentin ; Joëlle Dubois [France] ; Thierry Cresteil [France] ; Eric Folcher ; John N A. Hooper ; Dirk Erpenbeck ; William Aalbersberg ; Cécile Debitus

Source :

RBID : Hal:hal-00745061

Abstract

Four samples of Suberea ianthelliformis were investigated and furnished five new and 13 known brominated tyrosine-derived compounds. Two of the new compounds were identified as araplysillin N20-formamide and its N-oxide derivative. Three other new compounds, araplysillins IV, V, and VI, were isolated and identified as analogs of araplysillin II. Most of these compounds exhibit moderate inhibitory activities against chloroquine-resistant and -sensitive strains of Plasmodium falciparum, and were investigated for their PFTase inhibitory properties. The chemical content of the investigated sponges is correlated with their molecular phylogeny.


Url:
DOI: 10.1002/cbdv.201100309


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

Hal:hal-00745061

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888.</title>
<author>
<name sortKey="Mani, Luke" sort="Mani, Luke" uniqKey="Mani L" first="Luke" last="Mani">Luke Mani</name>
</author>
<author>
<name sortKey="Jullian, Valerie" sort="Jullian, Valerie" uniqKey="Jullian V" first="Valerie" last="Jullian">Valerie Jullian</name>
</author>
<author>
<name sortKey="Mourkazel, Beatrice" sort="Mourkazel, Beatrice" uniqKey="Mourkazel B" first="Beatrice" last="Mourkazel">Beatrice Mourkazel</name>
</author>
<author>
<name sortKey="Valentin, Alexis" sort="Valentin, Alexis" uniqKey="Valentin A" first="Alexis" last="Valentin">Alexis Valentin</name>
</author>
<author>
<name sortKey="Dubois, Joelle" sort="Dubois, Joelle" uniqKey="Dubois J" first="Joëlle" last="Dubois">Joëlle Dubois</name>
<affiliation wicri:level="1">
<hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">
<orgName>Institut de Chimie des Substances Naturelles</orgName>
<orgName type="acronym">ICSN</orgName>
<desc>
<address>
<addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation>
<relation name="UPR2301" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle name="UPR2301" active="#struct-441569" type="direct">
<org type="institution" xml:id="struct-441569" status="VALID">
<idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author>
<name sortKey="Cresteil, Thierry" sort="Cresteil, Thierry" uniqKey="Cresteil T" first="Thierry" last="Cresteil">Thierry Cresteil</name>
<affiliation wicri:level="1">
<hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">
<orgName>Institut de Chimie des Substances Naturelles</orgName>
<orgName type="acronym">ICSN</orgName>
<desc>
<address>
<addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation>
<relation name="UPR2301" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle name="UPR2301" active="#struct-441569" type="direct">
<org type="institution" xml:id="struct-441569" status="VALID">
<idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author>
<name sortKey="Folcher, Eric" sort="Folcher, Eric" uniqKey="Folcher E" first="Eric" last="Folcher">Eric Folcher</name>
</author>
<author>
<name sortKey="Hooper, John N A" sort="Hooper, John N A" uniqKey="Hooper J" first="John N A" last="Hooper">John N A. Hooper</name>
</author>
<author>
<name sortKey="Erpenbeck, Dirk" sort="Erpenbeck, Dirk" uniqKey="Erpenbeck D" first="Dirk" last="Erpenbeck">Dirk Erpenbeck</name>
</author>
<author>
<name sortKey="Aalbersberg, William" sort="Aalbersberg, William" uniqKey="Aalbersberg W" first="William" last="Aalbersberg">William Aalbersberg</name>
</author>
<author>
<name sortKey="Debitus, Cecile" sort="Debitus, Cecile" uniqKey="Debitus C" first="Cécile" last="Debitus">Cécile Debitus</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-00745061</idno>
<idno type="halId">hal-00745061</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00745061</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-00745061</idno>
<idno type="doi">10.1002/cbdv.201100309</idno>
<date when="2012-08">2012-08</date>
<idno type="wicri:Area/Hal/Corpus">000172</idno>
<idno type="wicri:Area/Hal/Curation">000172</idno>
<idno type="wicri:Area/Hal/Checkpoint">000146</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000146</idno>
<idno type="wicri:doubleKey">1612-1872:2012:Mani L:new:antiplasmodial:bromotyrosine</idno>
<idno type="wicri:Area/Main/Merge">001277</idno>
<idno type="wicri:Area/Main/Curation">001276</idno>
<idno type="wicri:Area/Main/Exploration">001276</idno>
<idno type="wicri:Area/France/Extraction">000210</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888.</title>
<author>
<name sortKey="Mani, Luke" sort="Mani, Luke" uniqKey="Mani L" first="Luke" last="Mani">Luke Mani</name>
</author>
<author>
<name sortKey="Jullian, Valerie" sort="Jullian, Valerie" uniqKey="Jullian V" first="Valerie" last="Jullian">Valerie Jullian</name>
</author>
<author>
<name sortKey="Mourkazel, Beatrice" sort="Mourkazel, Beatrice" uniqKey="Mourkazel B" first="Beatrice" last="Mourkazel">Beatrice Mourkazel</name>
</author>
<author>
<name sortKey="Valentin, Alexis" sort="Valentin, Alexis" uniqKey="Valentin A" first="Alexis" last="Valentin">Alexis Valentin</name>
</author>
<author>
<name sortKey="Dubois, Joelle" sort="Dubois, Joelle" uniqKey="Dubois J" first="Joëlle" last="Dubois">Joëlle Dubois</name>
<affiliation wicri:level="1">
<hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">
<orgName>Institut de Chimie des Substances Naturelles</orgName>
<orgName type="acronym">ICSN</orgName>
<desc>
<address>
<addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation>
<relation name="UPR2301" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle name="UPR2301" active="#struct-441569" type="direct">
<org type="institution" xml:id="struct-441569" status="VALID">
<idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author>
<name sortKey="Cresteil, Thierry" sort="Cresteil, Thierry" uniqKey="Cresteil T" first="Thierry" last="Cresteil">Thierry Cresteil</name>
<affiliation wicri:level="1">
<hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">
<orgName>Institut de Chimie des Substances Naturelles</orgName>
<orgName type="acronym">ICSN</orgName>
<desc>
<address>
<addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation>
<relation name="UPR2301" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle name="UPR2301" active="#struct-441569" type="direct">
<org type="institution" xml:id="struct-441569" status="VALID">
<idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author>
<name sortKey="Folcher, Eric" sort="Folcher, Eric" uniqKey="Folcher E" first="Eric" last="Folcher">Eric Folcher</name>
</author>
<author>
<name sortKey="Hooper, John N A" sort="Hooper, John N A" uniqKey="Hooper J" first="John N A" last="Hooper">John N A. Hooper</name>
</author>
<author>
<name sortKey="Erpenbeck, Dirk" sort="Erpenbeck, Dirk" uniqKey="Erpenbeck D" first="Dirk" last="Erpenbeck">Dirk Erpenbeck</name>
</author>
<author>
<name sortKey="Aalbersberg, William" sort="Aalbersberg, William" uniqKey="Aalbersberg W" first="William" last="Aalbersberg">William Aalbersberg</name>
</author>
<author>
<name sortKey="Debitus, Cecile" sort="Debitus, Cecile" uniqKey="Debitus C" first="Cécile" last="Debitus">Cécile Debitus</name>
</author>
</analytic>
<idno type="DOI">10.1002/cbdv.201100309</idno>
<series>
<title level="j">Chemistry and Biodiversity</title>
<idno type="ISSN">1612-1872</idno>
<imprint>
<date type="datePub">2012-08</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>Four samples of Suberea ianthelliformis were investigated and furnished five new and 13 known brominated tyrosine-derived compounds. Two of the new compounds were identified as araplysillin N20-formamide and its N-oxide derivative. Three other new compounds, araplysillins IV, V, and VI, were isolated and identified as analogs of araplysillin II. Most of these compounds exhibit moderate inhibitory activities against chloroquine-resistant and -sensitive strains of Plasmodium falciparum, and were investigated for their PFTase inhibitory properties. The chemical content of the investigated sponges is correlated with their molecular phylogeny.</p>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>France</li>
</country>
</list>
<tree>
<noCountry>
<name sortKey="Aalbersberg, William" sort="Aalbersberg, William" uniqKey="Aalbersberg W" first="William" last="Aalbersberg">William Aalbersberg</name>
<name sortKey="Debitus, Cecile" sort="Debitus, Cecile" uniqKey="Debitus C" first="Cécile" last="Debitus">Cécile Debitus</name>
<name sortKey="Erpenbeck, Dirk" sort="Erpenbeck, Dirk" uniqKey="Erpenbeck D" first="Dirk" last="Erpenbeck">Dirk Erpenbeck</name>
<name sortKey="Folcher, Eric" sort="Folcher, Eric" uniqKey="Folcher E" first="Eric" last="Folcher">Eric Folcher</name>
<name sortKey="Hooper, John N A" sort="Hooper, John N A" uniqKey="Hooper J" first="John N A" last="Hooper">John N A. Hooper</name>
<name sortKey="Jullian, Valerie" sort="Jullian, Valerie" uniqKey="Jullian V" first="Valerie" last="Jullian">Valerie Jullian</name>
<name sortKey="Mani, Luke" sort="Mani, Luke" uniqKey="Mani L" first="Luke" last="Mani">Luke Mani</name>
<name sortKey="Mourkazel, Beatrice" sort="Mourkazel, Beatrice" uniqKey="Mourkazel B" first="Beatrice" last="Mourkazel">Beatrice Mourkazel</name>
<name sortKey="Valentin, Alexis" sort="Valentin, Alexis" uniqKey="Valentin A" first="Alexis" last="Valentin">Alexis Valentin</name>
</noCountry>
<country name="France">
<noRegion>
<name sortKey="Dubois, Joelle" sort="Dubois, Joelle" uniqKey="Dubois J" first="Joëlle" last="Dubois">Joëlle Dubois</name>
</noRegion>
<name sortKey="Cresteil, Thierry" sort="Cresteil, Thierry" uniqKey="Cresteil T" first="Thierry" last="Cresteil">Thierry Cresteil</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000210 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000210 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     Hal:hal-00745061
   |texte=   New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888.
}}

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021